The value PSA test has been brought under question by an advisory panel in the United States, but for the time being, there are few options for prostate cancer screening. Dr. William Catalona, a pioneer in developing the PSA test, stresses its continued importance, even when considering its imperfections. He also discusses newer tests that are becoming available to confirm a prostate cancer diagnosis that may help reduce the need for biopsies including a Magnetic Resonance Imaging (MRI) technique, the Pro-PSA blood test (recently approved in the European Union) and the new PCA3 urine test, now approved by the FDA.