ADAMTS13, a protein, helps regulate clotting by cutting through von Willebrand factor, which catches platelets and helps them clot. Inhibiting ADAMTS13 can cause TTP (thrombotic thrombocytopenic purpura), a blood condition in which excessive clotting occurs in the body. For more information about clotting and other blood disorders, visit ASH's patient-information site http://www.BloodTheVitalConnection.org.
This animation was featured in the documentary film "Blood Detectives."
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